Malinovskaia V V, Khesin Ia E, Pokidysheva L N
Vopr Virusol. 1978 May-Jun(3):346-50.
In the presence of serum from newborn mice the cells of newborn mice produce almost no interferon induced by Newcastle disease virus. When cultivated in a medium containing adult mouse serum, interferon production by the cells increases markedly reaching the level of interferon production by the cells of adult animals. It is suggested that there are factors present in mouse serum which are capable, depending on the age of the animals, either of inhibiting or stimulating the activation of lysosomal apparatus and interferon production.
在新生小鼠血清存在的情况下，新生小鼠的细胞几乎不产生由新城疫病毒诱导的干扰素。当在含有成年小鼠血清的培养基中培养时，细胞的干扰素产量显著增加，达到成年动物细胞的干扰素产量水平。有人提出，小鼠血清中存在一些因子，这些因子根据动物的年龄，要么抑制要么刺激溶酶体装置的激活和干扰素的产生。
