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关于风险函数在乳腺癌研究中的应用。

On the use of hazard functions in breast cancer studies.

作者信息

Kay R, Scheurlen H, Schumacher M

出版信息

Experientia Suppl. 1982;41:118-30.

PMID:6958504
Abstract

Hazard functions are nowadays used extensively by mathematicians as a tool in the analysis of survival data. They have been implicitly employed in medicine for many years to investigate 'curability'. The hazard function will be shown to be a natural concept which can help the clinician to express in a precise way his ideas concerning the disease process and the biology of treatment effect. The relationship between hazard and survivor function is discussed. Some historical comments about the interpretation of statistics in survival time studies are also made.

摘要

如今,风险函数被数学家广泛用作分析生存数据的工具。多年来,它一直在医学中被隐含地用于研究“可治愈性”。风险函数将被证明是一个自然的概念,它可以帮助临床医生以精确的方式表达他对疾病过程和治疗效果生物学的看法。本文还讨论了风险函数与生存函数之间的关系。此外,还对生存时间研究中统计数据的解释作了一些历史性的评论。

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