Martin-Gousset D, Lawki F, Baudu P, Moreau P G
J Fr Ophtalmol. 1982;5(10):609-13.
Choriocapillaris occlusion is rare in leukemia. After Zimmerman in 1964 our case is the tenth published. A 20-year-old maghrebin male with documented acute lymphoblastic leukemia in relapse from two years was evaluated for sudden loss of vision Examination of the both fundus revealed a serous central retinal detachment. Our material consists in four fluorescein angiographies realized at 72 hours, 8th, 25th and 65th days. Initial aspect was numerous hyperfluorescent spots at the level of the pigment epithelium and following a bleb of serous detachment fullfiled of dye. The deep leakages were blown out after a week, when patient received anti-neoplasic drugs and corticoids. On the 25th Elschnig's spots appeared but a recurrence happened after two months. Unfortunately the eyes were not documented. Choroid is the most frequent ocular structure infiltrated in leukemia. On the other hand parallel may be done with Stern and Ernest experimentation (microspheres occlusion). Thus we considered that occurs infraction of choriocapillaris units by lymphoblasts or coagulopathy. Succed focal acute changes in Bruch's membrane and pigment epithelium.
脉络膜毛细血管阻塞在白血病中较为罕见。自1964年齐默尔曼报道后，我们的病例是第十例发表的。一名20岁的马格里布男性，有记录显示其急性淋巴细胞白血病复发两年，因突然视力丧失接受评估。双眼眼底检查发现浆液性中心性视网膜脱离。我们的资料包括在第72小时、第8天、第25天和第65天进行的四次荧光素血管造影。最初的表现是色素上皮水平有许多高荧光斑点，随后浆液性脱离的泡状区域充满染料。一周后，当患者接受抗肿瘤药物和皮质类固醇治疗时，深层渗漏消失。在第25天出现了埃尔施尼格斑，但两个月后复发。遗憾的是，眼部情况未留存记录。脉络膜是白血病中最常受浸润的眼部结构。另一方面，可以与斯特恩和欧内斯特的实验（微球阻塞）进行类比。因此，我们认为是淋巴细胞或凝血病导致脉络膜毛细血管单位梗死。随后在布鲁赫膜和色素上皮出现局灶性急性改变。
