Eversole L R, Leider A S, Alexander G
Oral Surg Oral Med Oral Pathol. 1982 Dec;54(6):663-7. doi: 10.1016/0030-4220(82)90081-0.
Keratoacanthoma (KA) is a relatively common skin lesion of questionable histogenic origin. Although cutaneous KAs are considered to arise from hair follicles, the rare cases reported occurring on mucous membranes would suggest possible origin from surface epithelium. A review of the literature revealed six previous cases involving oral mucosa. Seven new cases of keratoacanthoma are presented. Four occurred on the lower lip, and three arose from intraoral mucosal tissue, accounting for a total of nine reported intraoral cases.
角化棘皮瘤（KA）是一种组织发生来源存疑的相对常见的皮肤病变。尽管皮肤角化棘皮瘤被认为起源于毛囊，但报道的发生在黏膜上的罕见病例提示其可能起源于表面上皮。文献回顾显示之前有6例累及口腔黏膜的病例。本文报告了7例新的角化棘皮瘤病例。4例发生在下唇，3例起源于口腔黏膜组织，总计9例口腔内病例报道。
