Alho A
Ann Chir Gynaecol Suppl. 1982;196:31-6.
The fat embolism syndrome is defined as a variant of post-traumatic pulmonary insufficiency complicating musculoskeletal trauma. It occurs up to 28% of cases depending to a certain extent on the magnitude of the trauma. Tissue fat embolization into pulmonary and other capillaries and microthrombus formation appear to be the factors causing the microvascular disorder in the lungs, brain, kidneys, skin etc. Pulmonary malfunction and respiratory distress is the most important part of the fat embolism syndrome. The cornerstone of treatment is in supporting respiratory care. Early and effective stabilization of fractures and pharmacological glucocorticoid therapy appear to be beneficial. The syndrome is usually self-resolving after several days. The central clinical problem is early detection of the syndrome.
脂肪栓塞综合征被定义为创伤后肺功能不全的一种变体，常并发于肌肉骨骼创伤。其发生率高达28%，在一定程度上取决于创伤的严重程度。组织脂肪栓塞至肺及其他毛细血管，并形成微血栓，这些似乎是导致肺、脑、肾、皮肤等部位微血管功能障碍的因素。肺功能障碍和呼吸窘迫是脂肪栓塞综合征最重要的部分。治疗的关键在于支持呼吸护理。早期有效固定骨折以及使用糖皮质激素进行药物治疗似乎有益。该综合征通常在数天后自行缓解。核心临床问题是早期发现该综合征。
