Rasminsky M
Electroencephalogr Clin Neurophysiol Suppl. 1982;36:99-105.
In the spinal root axons of dystrophic mice conduction of nerve impulses is slow and either saltatory or continuous, presumably corresponding to areas of myelination and amyelination respectively. These abnormally myelinated axons contain foci of hyperexcitability manifested by spontaneous ectopic excitation, ephaptic excitation and autoexcitation. Similar phenomena in demyelinated central and peripheral nerve fibres may underly positive neurological symptomatology in human peripheral and central demyelinating diseases (Rasminsky 1981, 1982).
在营养不良小鼠的脊神经根轴突中，神经冲动的传导缓慢，呈跳跃式或连续式，推测分别对应有髓鞘和无髓鞘区域。这些异常髓鞘化的轴突含有过度兴奋性病灶，表现为自发异位兴奋、ephaptic兴奋和自发放电。脱髓鞘的中枢和外周神经纤维中的类似现象可能是人类外周和中枢脱髓鞘疾病中阳性神经症状的基础（拉斯明斯基，1981年、1982年）。
