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[使用口服前列腺素E2进行引产]

[Elective induction of labor using oral PGE2].

作者信息

Merveille J J, Godefroid L, Pestiau J

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1982;11(7):877-84.

PMID:6962225
Abstract

100 inductions of labour were attempted in 98 patients by administration of tablets of Prostaglandin E2. 12 inductions were dropped from the study to achieve an homogeneous population of 88 patients filling the criteria of elective induction of labour at term. All these inductions were attempted under electronic monitoring and according to a fixed dosage schedule. Low amniotomy was performed only in presence of advancing labour. Oral prostaglandin E2 successfully induced labour in 92%. The digestive side-effects were the most frequently encountered (34%). 5 cases of uterine hyperstimulation were recorded without fetal repercussion at birth. The procedure was considered safe for the fetus and the newborn as demonstrated by monitoring and clinical evaluation (Apgar score).

摘要

通过给予前列腺素E2片剂,对98例患者尝试进行了100次引产。为了使88例符合足月选择性引产标准的患者构成同质群体,有12例引产被排除在研究之外。所有这些引产均在电子监测下并按照固定剂量方案进行。仅在产程进展时进行低位破膜。口服前列腺素E2成功引产率为92%。消化系统副作用最为常见(34%)。记录到5例子宫过度刺激,出生时未对胎儿造成影响。通过监测和临床评估(阿氏评分)表明,该 procedure 对胎儿和新生儿是安全的。

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