Taylor T B, Pemstein R, Loy R G
J Reprod Fertil Suppl. 1982;32:219-24.
Two trials were conducted to (1) determine the degree of control of ovulation achieved by treating mares in late winter with progesterone and oestradiol-17 beta combined after prior exposure to an artificially increased photoperiod, and (2) to examine the effectiveness of such a procedure incorporated into equine breeding farm management systems. Following a 15-day treatment of 150 mg progesterone and 10 mg oestradiol-17 beta daily with 10 mg PGF-2 alpha on the last day of steroid treatment, 27 of 31 mares ovulated on Days 8-14 after the last injection in one trial. Conception rate for mares mated during that period was 77%, compared with 50% in untreated mares mated at first oestrus following the treatment period. In a second, larger field trial involving the same treatment for a 10-day period, 103 of 128 mares ovulated on Days 9-16 after the last injection and 62% of the mares mated on those days conceived. These results indicate that the combined steroid treatment provided reasonably precise and practical control of ovulation time in mares adequately stimulated by increased photoperiod without detrimental effect on fertility.
进行了两项试验，一是确定在早春对母马先进行人工延长光照周期处理后，用孕酮和雌二醇 -17β联合治疗所达到的排卵控制程度；二是检验将此程序纳入马养殖场管理系统的有效性。在为期15天的治疗中，每天给予150毫克孕酮和10毫克雌二醇 -17β，并在类固醇治疗的最后一天给予10毫克前列腺素F2α，在一项试验中，31匹母马中有27匹在最后一次注射后的第8 - 14天排卵。在此期间配种的母马受孕率为77%，相比之下，在治疗期后的首次发情期未治疗的母马配种受孕率为50%。在第二项更大规模的田间试验中，采用相同治疗方法为期10天，128匹母马中有103匹在最后一次注射后的第9 - 16天排卵，在这些天配种的母马中有62%受孕。这些结果表明，联合类固醇治疗对光照周期延长充分刺激的母马排卵时间提供了合理精确且实用的控制，且对生育力无不利影响。
