Woods G L, Ginther O J
J Reprod Fertil Suppl. 1982;32:415-21.
The ability of a pituitary extract to induce ovulation and the effect of multiple ovulations on pregnancy rate and incidence of multiple fetuses were studied in seasonally anovulatory mares. The extract induced ovulation in 95% of mares having a greater than or equal to 25 mm follicle at the onset of treatment and in 64% the ovulations were multiple. The extract was less effective when the largest initial follicle was less than 25 mm. Approximately 50% of the treated mares that ovulated did not become pregnant or enter prolonged dioestrus before returning to an anovulatory condition. In treated mares with one ovulation the pregnancy rate (33%) was lower than in controls (60%) and was further reduced in mares with greater than 2 ovulations. There was a pronounced discrepancy between the number of palpated conceptuses and number of palpated ovulations. Only one conceptus and one fetus was found on Days 28 and 50, respectively, in every pregnant mare (11 treated, 1 control) in which multiple ovulations were palpated.
研究了垂体提取物诱导季节性无排卵母马排卵的能力以及多次排卵对妊娠率和多胎发生率的影响。在治疗开始时，提取物在95%卵泡直径大于或等于25毫米的母马中诱导排卵，其中64%为多次排卵。当最大初始卵泡小于25毫米时，提取物效果较差。约50%排卵的经治疗母马在恢复到无排卵状态之前未怀孕或进入延长的间情期。在经治疗的单次排卵母马中，妊娠率（33%）低于对照组（60%），且在排卵超过2次的母马中进一步降低。触诊到的孕体数量与触诊到的排卵数量之间存在明显差异。在每匹触诊到多次排卵的怀孕母马（11匹经治疗，1匹对照）中，分别在第28天和第50天仅发现一个孕体和一个胎儿。
