Forsberg C M
Swed Dent J Suppl. 1982;15:37-40.
The effect of 50 per cent phosphoric acid on oral soft tissue was studied in two investigations. In the first investigation the buccal mucosa of three rats was studied after contact with phosphoric acid for 1, 5 and 10 minutes respectively. The material of the second investigation comprised of 26 patients from whom 31 pairs of premolars were planned to be extracted for orthodontic reasons. Phosphoric acid was applied for 90 seconds on one tooth and its buccal gingival margin in each pair of teeth. After a period varying between 1 and 7 days the tooth and a section of the gingiva were extracted and prepared for microscopic examination. The second tooth in each pair was the control tooth. The study showed that only a relatively long acid application time resulted in obvious histologic changes in the mucous membrane. The phosphoric acid gave no demonstrable gingival reaction in the patients.
两项研究探讨了50%磷酸对口腔软组织的影响。在第一项研究中，分别使三只大鼠的颊黏膜与磷酸接触1分钟、5分钟和10分钟后进行观察。第二项研究的对象为26例患者，出于正畸原因计划拔除31对前磨牙。在每对牙齿中的一颗牙齿及其颊侧牙龈边缘涂抹磷酸90秒。1至7天后，拔除牙齿及部分牙龈组织，准备进行显微镜检查。每对牙齿中的另一颗作为对照牙。研究表明，只有酸的作用时间相对较长时，才会导致黏膜出现明显的组织学变化。在患者中，磷酸未引起明显的牙龈反应。
