对膀胱癌患者进行肿瘤相关淋巴细胞介导的细胞毒性检测的随访研究。
A follow-up study of urinary bladder patients tested for tumour-related lymphocyte-mediated cytotoxicity.
作者信息
Larsson A, Näslund I, Troye M
机构信息
Department of Immunology, University of Stockholm, Sweden.
出版信息
Cancer Immunol Immunother. 1982;14(2):82-5. doi: 10.1007/BF00200172.
A total of 143 patients with transitional cell carcinoma of the urinary bladder were tested for lymphocyte-mediated cytotoxicity against the bladder carcinoma cell line T24. Some of the patients were also tested against MANO (another cell line of transitional cell bladder carcinoma origin), HCV29 (from bladder epithelium, probably transformed in vitro) and/or HT29 (from a colon adenocarcinoma). The patients were divided into a high- or a low-responder group for each cell line. The patients were followed up and the correlation between a high response in the cytotoxicity tests and survival was evaluated using an adaptation of the Mantel-Haenszel statistics. No significant correlation could be demonstrated.
对总共143例膀胱移行细胞癌患者进行了针对膀胱癌细胞系T24的淋巴细胞介导的细胞毒性检测。部分患者还接受了针对MANO（另一种源自膀胱移行细胞癌的细胞系）、HCV29（来自膀胱上皮，可能在体外转化）和/或HT29（来自结肠腺癌）的检测。针对每个细胞系，将患者分为高反应组或低反应组。对患者进行随访，并采用Mantel-Haenszel统计方法的一种变体来评估细胞毒性检测中的高反应与生存率之间的相关性。未发现显著相关性。
Zotero 插件