Hakkarainen J, Lindberg P, Bengtsson G, Jönsson L
Acta Vet Scand. 1978;19(2):285-97. doi: 10.1186/BF03547633.
By using a therapeutic dietary supplementation in pigs, which had developed the vitamin Ε and selenium deficiency (VESD) syndrome, the same amounts of α-tocopheryl acetate and selenium were found to be effective as under prophylactic conditions. The experiment thus supported the conclusions that the addition of 5 mg DL-α-tocopheryl acetate/kg and 135 μg selenium/kg to a diet, which contained only traces of vitamin Ε and selenium, represents a level of minimal requirement. Glutathione peroxidase activity in blood serum was used to evaluate the selenium status in pigs. A modified method for determination of tocopherol in fat tissue was described. The addition of 15 mg α-tocopheryl acetate/kg diet was demonstrated to be sufficient to maintain the tocopherol stores in body fat at an unchanged level.
通过对已出现维生素E和硒缺乏（VESD）综合征的猪使用治疗性膳食补充剂，发现相同剂量的醋酸α-生育酚和硒与预防性条件下一样有效。该实验因此支持了以下结论：在仅含有微量维生素E和硒的日粮中添加5毫克DL-α-生育酚醋酸酯/千克和135微克硒/千克代表了最低需求量水平。血清中的谷胱甘肽过氧化物酶活性用于评估猪的硒状态。描述了一种测定脂肪组织中生育酚的改良方法。已证明在日粮中添加15毫克α-生育酚醋酸酯/千克足以使体脂中的生育酚储备维持在不变水平。
