Fowler B N, Jacobs M L, Zir L, Dinsmore R E, Vezeridis M P, Daggett W M
J Thorac Cardiovasc Surg. 1980 Feb;79(2):288-93.
One hundred six consecutive patients underwent elective or emergency coronary artery bypass grafting (CABG) between January, 1974, and November, 1975. There were 90 men of an average age of 54 years and 16 women an average of 64 years. Unstable angina (preinfarction angina, angina decubitus, and crescendo angina) was present in 54 patients of this group and eight were in congestive heart failure. Sixty-two of the 106 had previously had myocardial infarctions and four had evolving infarctions. There were four operative deaths (3.8%) and one early hospital death (less than 30 days' hospitalization). Perioperative infarction occurred in five of the survivors. Of the 197 grafts placed in the 101 survivors, 94% were patent by angiography at 1 to 2 weeks (175 of 187 vein grafts and 10 of 10 left internal mammary grafts). At 1 to 2 years after CABG, 62% of the survivors consented to repeat angiography at which time 94% of the grafts were patent (101 of 108 vein grafts and seven of seven left internal mammary grafts). Clinical follow-up of 81 of the 101 survivors at 1 year found 99% of them to be asymptomatic or improved. Repeat clinical follow-up of all survivors (99 of 101) at 3 to 4 years found 93.9% asymptomatic or improved. Overall survival, including operative deaths, was 92.4% at 4 years.
1974年1月至1975年11月期间,106例连续患者接受了择期或急诊冠状动脉旁路移植术(CABG)。其中有90名男性,平均年龄54岁,16名女性,平均年龄64岁。该组中有54例患者存在不稳定型心绞痛(梗死前心绞痛、卧位型心绞痛和进行性加重型心绞痛),8例患者患有充血性心力衰竭。106例患者中有62例曾发生过心肌梗死,4例有进展性梗死。有4例手术死亡(3.8%)和1例早期医院死亡(住院时间少于30天)。围手术期梗死发生在5名幸存者中。在101名幸存者中植入的197根移植物中,1至2周时血管造影显示94%通畅(187根静脉移植物中的175根和10根左乳内动脉移植物中的10根)。冠状动脉旁路移植术后1至2年,62%的幸存者同意再次进行血管造影,此时94%的移植物通畅(108根静脉移植物中的101根和7根左乳内动脉移植物中的7根)。对101名幸存者中的81名进行1年的临床随访发现,99%的患者无症状或病情改善。对所有幸存者(101名中的99名)进行3至4年的重复临床随访发现,93.9%的患者无症状或病情改善。包括手术死亡在内的4年总生存率为92.4%。