Martínez Cairo S, Muñóz O, Calderón M E, Alanis F, Alvarez M T, Fierro H
Bol Med Hosp Infant Mex. 1980 Jan-Feb;37(1):93-106.
A longitudinal study was carried out in 40 patients with typhoid fever, 21 with infectious hepatitis and 15 with amebic liver abscess in order to determine percentual values of lymphocytes T and B in relation with age and nutritional state as compared to a normal control group. In patients with typhoid fever, a decrease of percentual values of lymphocytes T was observed starting on the second week of evolution with intensification on the third week, predominating in patients less than seven years of age and in malnourished cases (p less than 0.001) and late recovery in the group of patients less than seven years old. In patients with acute infectious hepatitis, there was depression of lymphocytes T that persisted to the eighth week and was independent of age, but more severe in the malnourished (p less than 0.001). In cases with amebic liver abscess, depression of lymphocytes T was observed during the first six weeks of evolution without relation with age or the state of nutrition, but with increased slowliness in recovery in patients under seven years. There were no disturbances in lymphocytes B nor in cutaneous response to dinitrofluorobencene (DNFB) in the three groups of patients.
对40例伤寒患者、21例传染性肝炎患者和15例阿米巴肝脓肿患者进行了一项纵向研究，以确定与正常对照组相比，T淋巴细胞和B淋巴细胞的百分比值与年龄和营养状况的关系。在伤寒患者中，从病程第二周开始观察到T淋巴细胞百分比值下降，第三周加剧，在7岁以下患者和营养不良病例中更为明显（p<0.001），且7岁以下患者组恢复较晚。在急性传染性肝炎患者中，T淋巴细胞有抑制，持续到第八周，且与年龄无关，但在营养不良患者中更严重（p<0.001）。在阿米巴肝脓肿病例中，病程的前六周观察到T淋巴细胞有抑制，与年龄或营养状况无关，但7岁以下患者恢复较慢。三组患者的B淋巴细胞及对二硝基氟苯（DNFB）的皮肤反应均无异常。
