Weimert T A, Yoder M G
Laryngoscope. 1980 Apr;90(4):667-72. doi: 10.1288/00005537-198004000-00014.
Despite the widespread use of prophylactic antibiotics in nasal surgery, the subject has been paid little attention in the literature. In a retrospective analysis of 210 patients who underwent septal surgery or a rhinoplasty, only 5 developed minor infections. Patients undergoing septal surgery or rhinoplasty (174) were evaluated in a randomized sequence, prospectively, to study the efficacy of systemic antibiotic prophylaxis. Only 4 patients developed minor infections; and 173 patients demonstrated no clinical nor radiographic evidence of subsequent sinusitis. The incidence of infectious complications resulting from intranasal surgery is not sufficient to warrant the use of prophylactic antibiotics. Furthermore, proof of their effectiveness in preventing such infections is lacking.
尽管预防性抗生素在鼻腔手术中被广泛使用，但该主题在文献中却很少受到关注。在一项对210例行鼻中隔手术或鼻整形术患者的回顾性分析中，只有5例发生了轻微感染。对行鼻中隔手术或鼻整形术的174例患者进行了前瞻性随机序列评估，以研究全身性抗生素预防的效果。只有4例患者发生了轻微感染；173例患者未表现出随后鼻窦炎的临床或影像学证据。鼻内手术引起的感染并发症发生率不足以保证使用预防性抗生素。此外，缺乏其预防此类感染有效性的证据。
