Marni A, Aseni P, Grassi G, Spada G, Belli L
Minerva Chir. 1980 Apr 30;35(8):543-6.
The effect of the distal spleno-renal shunt on hypersplenism has been investigated on 19 out of 20 patients undergoing this procedure at the 2nd Department of Surgery Pizzamiglio, Niguarda Hospital of Milan. 6 patients had an hypersplenism of high degree (platelet count less than 50;000/mm3), 11 of moderate degree (platelet count greater than or equal to 50,000 and less than 100,000/mm3) and 2 of low degree (platelet count greater than 100,000 and less than 100,000/mm3). Platelet count significantly improved after the operation (p less than 0.01) and hypersplenism resulted cured or ameliorated in 17 out of 19 patients under study. After briefly discussing the pathogenesis of hypersplenism in patients bearing portal hypertension, the A. conclude that hypersplenism also severe is not "per se" a contraindication to Warren shunt.
米兰尼瓜尔达医院皮扎米廖外科第二科室对20例接受远端脾肾分流术的患者中的19例，研究了该手术对脾功能亢进的影响。6例患者为高度脾功能亢进（血小板计数低于50,000/mm³），11例为中度脾功能亢进（血小板计数大于或等于50,000且小于100,000/mm³），2例为低度脾功能亢进（血小板计数大于100,000且小于100,000/mm³）。术后血小板计数显著改善（p<0.01），19例研究患者中有17例脾功能亢进得到治愈或改善。在简要讨论了门静脉高压患者脾功能亢进的发病机制后，作者得出结论，即使是严重的脾功能亢进本身也不是沃伦分流术的禁忌症。
