Hill R C, Chitwood W R, Sink J D, Cox J L, Wechsler A S
Arch Surg. 1980 May;115(5):609-14. doi: 10.1001/archsurg.1980.01380050033008.
Direct on-line assessment of postoperative ventricular function has not been possible. We assessed the feasibility of using pulse-transit sonomicrometry to measure regional function in man postoperatively. Ultrasonic transducers (3 mm in diameter) were implanted along the minor axis of the left ventricle at midwall depth into a region supplied by a bypass graft. All wires were tunneled subcutaneously. Pressures, ECG, and regional dimensions were monitored in eight patients continuously, and at 48 to 72 hours postoperatively, the effects of sodium nitroprusside were assessed. The transducers were withdrawn with no complications. Nitroprusside was associated with an increase in systolic shortening from 1.60 +/- 0.19 to 1.92 +/- 0.25 mm and rate of shortening from 12.13 +/- 1.85 to 15.34 +/- 2.38 mm/s at constant end-diastolic lengths. Using this technique for recording regional dimensions, nitroprusside therapy augmented function at a constant preload.
术后对心室功能进行直接在线评估尚无可能。我们评估了使用脉冲传输超声测微术测量人体术后局部功能的可行性。将直径3毫米的超声换能器沿左心室短轴植入至中壁深度，置于旁路移植血管供血的区域。所有导线均经皮下穿出。对8例患者持续监测压力、心电图和局部尺寸，并在术后48至72小时评估硝普钠的作用。换能器取出时无并发症发生。在舒张末期长度恒定的情况下，硝普钠使收缩期缩短从1.60±0.19毫米增加至1.92±0.25毫米，缩短速率从12.13±1.85毫米/秒增加至15.34±2.38毫米/秒。使用该技术记录局部尺寸时，硝普钠治疗在恒定前负荷下增强了功能。
