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Immune thrombocytopenia induced by cotrimoxazole.

作者信息

Barr A L, Whineray M

出版信息

Aust N Z J Med. 1980 Feb;10(1):54-5. doi: 10.1111/j.1445-5994.1980.tb03420.x.

Abstract

Cotrimoxazole administration is occasionally associated with thrombocytopenia. Interference with folate metabolism has been postulated. The drug has also been postulated to induce an autoantibody by acting as a hapten, but proof has not been forthcoming. A case is reported in which the serum has been shown to contain an anti-platelet autoantibody requiring sulphamethoxazole or cotrimoxazole for activity.

摘要

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