Lampson L A, Levy R
J Immunol. 1980 Jul;125(1):293-9.
Evidence is presented for two populations of Ia-like molecules on the human B cell line Raji. Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic determinants on B cell antigens. Both immunoprecipitate 34,000- and 28,000-dalton material from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well. Immunodepletion experiments confirm that the antibodies react with two different populations of molecules.
有证据表明人类B细胞系Raji上存在两类Ia样分子。文中描述了两种单克隆抗体L203和L227。二者均识别B细胞抗原上的非多态性决定簇。二者都能从125I标记的Raji提取物中免疫沉淀出34,000道尔顿和28,000道尔顿的物质，但L227还能沉淀出25,000道尔顿的物质。免疫去除实验证实这两种抗体与两类不同的分子发生反应。
