Hart W R, Craig J R
Am J Clin Pathol. 1978 Aug;70(2):217-23. doi: 10.1093/ajcp/70.2.217.
The authors report the clinicopathologic findings in four cases of adult women with rhabdomyosarcomas that originated in the endometrium or cervix, or both. All tumors were pure sarcomas and not components of carcinosarcomas or malignant mixed mesodermal tumors. In two patients, the tumors were typical botryoid embryonal rhabdomyosarcomas. Both patients were alive and well following combined treatments with surgery and chemotherapy or irradiation 3.0 and 2.7 years after operation, respectively, although one had a solitary pulmonary metastasis resected. The other two women had pleomorphic rhabdomyosarcomas, and both died rapidly of widespread tumor. Combination therapy rather than surgery alone probably should be used initially for patients with rhabdomyosarcomas of the uterus.
作者报告了4例成年女性横纹肌肉瘤的临床病理结果，这些肿瘤起源于子宫内膜或宫颈，或两者皆有。所有肿瘤均为纯肉瘤，而非癌肉瘤或恶性混合中胚层肿瘤的组成部分。两名患者的肿瘤为典型的葡萄状胚胎性横纹肌肉瘤。两名患者分别在术后3.0年和2.7年接受手术及化疗或放疗联合治疗后存活且状况良好，尽管其中一人有一个孤立性肺转移灶被切除。另外两名女性患有多形性横纹肌肉瘤，两人均因肿瘤广泛转移而迅速死亡。对于子宫横纹肌肉瘤患者，最初可能应采用联合治疗而非单纯手术治疗。
