• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Receptor binding of B-norsteroids.

作者信息

Stárka L, Alexandrová M, Hampl R, Sanda V

出版信息

Endocrinol Exp. 1980 Mar;14(1):45-9.

PMID:6967400
Abstract

The binding of B-nor-analogues of glucocorticoids, estrogens and of an androgen to specific cytosol receptors was compared with that of parent compounds of the normal series. In the study of binding of B-norcortisol and related compounds rat liver cytosol was used, while in a case of B-norestrogens rat uterus cytosol and for 17 alpha-methyl-B-nortestosterone rat prostate cytosol was used. The displacement of the appropriate radioligands by B-norsteroids was remarkably lower than that caused by correspondinga steroids with normal B-ring with the exception of 17 alpha-methyl-B-nortestosterone.

摘要

相似文献

1
Receptor binding of B-norsteroids.
Endocrinol Exp. 1980 Mar;14(1):45-9.
2
[Estradiol receptors in rat kidney, liver and uterus cytosol].[大鼠肾脏、肝脏和子宫胞质溶胶中的雌二醇受体]
Dokl Akad Nauk SSSR. 1975 Jan-Feb;220(1):244-7.
3
19-nor analogs of adrenal steroids: mineralocorticoid and glucocorticoid receptor activity.肾上腺皮质激素的19-去甲类似物:盐皮质激素和糖皮质激素受体活性
Endocrinology. 1980 Nov;107(5):1278-80. doi: 10.1210/endo-107-5-1278.
4
Tissue-specific pharmacology of testosterone and 5 alpha-dihydrotestosterone analogues: characterization of a novel canine liver androgen-binding protein.
Mol Pharmacol. 1995 May;47(5):1080-8.
5
Different binding of testosterone, 19-nortestosterone and their 5 alpha-reduced derivatives to the androgen receptor of the rat seminal vesicle: a step toward the understanding of the anabolic action of nortesterone.
Endokrinologie. 1982 Oct;80(2):163-72.
6
Steroid hormone receptor studies in melanoma model systems.黑色素瘤模型系统中的类固醇激素受体研究。
J Supramol Struct. 1980;13(1):35-46. doi: 10.1002/jss.400130104.
7
Proceedings: Specificity of oestradiol high-affinity binding in cytosol from the brain and pituitary of the rat.论文集:大鼠脑和垂体胞质溶胶中雌二醇高亲和力结合的特异性
J Endocrinol. 1974 Apr;61(1):23-4.
8
[Hydrocortisone-receptor complex binding with various nonhistone protein groups].[氢化可的松 - 受体复合物与各种非组蛋白蛋白基团的结合]
Vopr Med Khim. 1980 Sep-Oct;26(5):656-9.
9
7 alpha-Methyl-17 alpha-(E-2'-[125I]iodovinyl)-19-nortestosterone: a new radioligand for the detection of androgen receptor.7α-甲基-17α-(E-2'-[¹²⁵I]碘乙烯基)-19-去甲睾酮:一种用于检测雄激素受体的新型放射性配体。
Steroids. 1993 Jan;58(1):13-23. doi: 10.1016/0039-128x(93)90012-c.
10
Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens.B环、C环和D环取代的雌二醇羧酸酯作为局部活性雌激素的合成与评价
J Med Chem. 2003 May 8;46(10):1886-904. doi: 10.1021/jm0204340.