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即将发生的主动脉肠瘘出血:早期识别对改善预后的影响。

Impending aortoenteric hemorrhage: the effect of early recognition on improved outcome.

作者信息

Perdue G D, Smith R B, Ansley J D, Costantino M J

出版信息

Ann Surg. 1980 Aug;192(2):237-43. doi: 10.1097/00000658-198008000-00019.

Abstract

Aortoenteric hemorrhage is the result of enteric erosion and necrosis of aortic wall or anastomotic site. Mechanical or bacteriologic causes may occur singly or in combination. The temporal sequence is such that warning symptoms, often including back pain, fever, hemotochezia, and anemia, are present long before exsanguinating hemorrhage occurs. Vigorous diagnostic efforts, including gallium-67 citrate nuclear scan and computerized axial tomography, lead to a correct diagnosis. This allows planned semielective corrective operation before severe hemorrhage begins. The ideal operation consists of extra-anatomic revascularization, excision of the infected prosthesis, bowel repair with decompression, and sump drainage. Appropriate antimicrobial therapy should be continued until healing is complete. With aggressive diagnostic and therapeutic intervention according to this plan, marked improvement in survival and limb preservation can be anticipated in patients having this complication of aortic surgery. In this series, 15 of 18 patiets having operation recovered, though delayed limb loss occurred in two.

摘要

主动脉肠瘘出血是主动脉壁或吻合口处肠道侵蚀和坏死的结果。机械性或细菌性病因可能单独或合并出现。其时间顺序是,在发生致命性出血之前很长时间就会出现警示症状,通常包括背痛、发热、便血和贫血。积极的诊断措施,包括枸橼酸镓-67核素扫描和计算机断层扫描,可得出正确诊断。这使得在严重出血开始前能够进行计划性的半选择性矫正手术。理想的手术包括解剖外血管重建、切除感染的假体、肠道减压修复和引流。应持续进行适当的抗菌治疗直至完全愈合。按照该方案进行积极的诊断和治疗干预,预计患有主动脉手术这种并发症的患者在生存率和肢体保留方面会有显著改善。在本系列中,18例接受手术的患者中有15例康复,不过有2例出现了延迟性肢体丧失。

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本文引用的文献

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Arch Surg. 1962 Oct;85:650-62. doi: 10.1001/archsurg.1962.01310040122014.
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