Komp D M, El Mahdi A, Starling K A, Easley J, Vietti T J, Berry D H, George S L
Med Pediatr Oncol. 1980;8(1):35-40. doi: 10.1002/mpo.2950080106.
Sixty children survived for five years after the diagnosis of histiocytosis X. Serious disabilities were seen in 50% of children whose disease involved soft tissue and bone. Late deaths from pulmonary failure were associated with opportunistic infections in two cases. Future treatment approaches must weigh the risks of therapy-related complications against the probability of significant disability if the disease continues for many years.
60名儿童在被诊断为勒-雪病后存活了5年。在疾病累及软组织和骨骼的儿童中，50%出现了严重残疾。两例因呼吸衰竭导致的晚期死亡与机会性感染有关。未来的治疗方法必须权衡治疗相关并发症的风险与如果疾病持续多年出现严重残疾的可能性。
