Dewar G J, Lim C N, Michalyshyn B, Akabutu J
Can J Surg. 1981 Jan;24(1):67-71.
Between July 1, 1972 and June 30, 1977, 541 leukemic patients were admitted to the University Hospital in Edmonton. Eight of 11 patients who underwent emergency operation for complications of leukemia or antileukemic therapy died within 30 days of operation. Six cases are reviewed to illustrate the four basic types of gastrointestinal lesions and complications of leukemia: hemorrhagic and agranulocytic necrosis, leukemic infiltrates and fungal lesions. A fifth type which is a mixture of the four basic types was also noted. As a result of their experience and a review of the literature the authors believe that an aggressive approach, consisting of close monitoring and early laparotomy combined with vigorous supportive therapy, should be used when dealing with suspected gastrointestinal complications in leukemic patients.
1972年7月1日至1977年6月30日期间，541名白血病患者住进了埃德蒙顿大学医院。11名因白血病并发症或抗白血病治疗而接受急诊手术的患者中有8例在术后30天内死亡。现回顾6例病例以阐明白血病胃肠道病变及并发症的四种基本类型：出血性和粒细胞缺乏性坏死、白血病浸润及真菌性病变。还发现了一种为四种基本类型混合的第五种类型。基于他们的经验及文献回顾，作者认为在处理白血病患者疑似胃肠道并发症时，应采用积极的方法，包括密切监测、早期剖腹手术并辅以积极的支持治疗。
