Cicciarelli J C, Terasaki P I, Iwaki Y, Billing R, Yamaguchi T, Takahashi H, Starzl T
Clin Immunol Immunopathol. 1981 Jan;18(1):32-8. doi: 10.1016/0090-1229(81)90004-0.
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks. These cells were demonstrated by showing that T cells isolated by sheep red cell rosetting were killed by the action of rabbit anti-B-cell sera and of HLA-DR antisera. The HLA-DR specificities found on the T cells corresponded with those on the patients’ B lymphocytes.
在接受长期引流的患者胸导管淋巴液中,具有DR抗原的T细胞数量众多。随着引流的进行,淋巴液中T DR细胞的比例在6周时增加到高达70%的水平。通过证明经绵羊红细胞玫瑰花结分离的T细胞可被兔抗B细胞血清和HLA-DR抗血清作用所杀伤,证实了这些细胞的存在。在T细胞上发现的HLA-DR特异性与患者B淋巴细胞上的特异性相对应。