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胸导管淋巴液中携带DR的T淋巴细胞

DR-bearing T lymphocytes in thoracic duct lymph.

作者信息

Cicciarelli J C, Terasaki P I, Iwaki Y, Billing R, Yamaguchi T, Takahashi H, Starzl T

出版信息

Clin Immunol Immunopathol. 1981 Jan;18(1):32-8. doi: 10.1016/0090-1229(81)90004-0.

Abstract

T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks. These cells were demonstrated by showing that T cells isolated by sheep red cell rosetting were killed by the action of rabbit anti-B-cell sera and of HLA-DR antisera. The HLA-DR specificities found on the T cells corresponded with those on the patients’ B lymphocytes.

摘要

在接受长期引流的患者胸导管淋巴液中,具有DR抗原的T细胞数量众多。随着引流的进行,淋巴液中T DR细胞的比例在6周时增加到高达70%的水平。通过证明经绵羊红细胞玫瑰花结分离的T细胞可被兔抗B细胞血清和HLA-DR抗血清作用所杀伤,证实了这些细胞的存在。在T细胞上发现的HLA-DR特异性与患者B淋巴细胞上的特异性相对应。

相似文献

1
DR-bearing T lymphocytes in thoracic duct lymph.胸导管淋巴液中携带DR的T淋巴细胞
Clin Immunol Immunopathol. 1981 Jan;18(1):32-8. doi: 10.1016/0090-1229(81)90004-0.

本文引用的文献

7
Effect of cross reactions on HL-A antigen immunogenicity.
Tissue Antigens. 1974;4(2):136-45. doi: 10.1111/j.1399-0039.1974.tb00234.x.
10
Drainage of thoracic duct lymph in renal transplant patients.
Transplantation. 1976 Feb;21(2):133-40. doi: 10.1097/00007890-197602000-00008.

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