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使用氧-15和正电子发射断层扫描技术对正常人体局部脑氧利用和血流情况的研究

Regional cerebral oxygen utilization and blood flow in normal man using oxygen-15 and positron emission tomography.

作者信息

Frackowiak R S, Jones T, Lenzi G L, Heather J D

出版信息

Acta Neurol Scand. 1980 Dec;62(6):336-44. doi: 10.1111/j.1600-0404.1980.tb03046.x.

DOI:10.1111/j.1600-0404.1980.tb03046.x
PMID:6970494
Abstract

Quantitative determination of regional cerebral blood flow (rCBF), regional cerebral oxygen utilization (rCMRO2) and regional oxygen extraction ratio (rOER) was performed in 11 normal volunteers by an oxygen 15 inhalation method and positron emission tomography. Regional values comparable with figures from the literature have been obtained. This non-invasive approach offers the possibility of a simultaneous quantitative evaluation of these physiological parameters in health and disease.

摘要

通过氧-15吸入法和正电子发射断层扫描术，对11名正常志愿者进行了局部脑血流量（rCBF）、局部脑氧利用率（rCMRO2）和局部氧摄取率（rOER）的定量测定。已获得与文献数据相当的局部数值。这种非侵入性方法为在健康和疾病状态下同时定量评估这些生理参数提供了可能。

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