Claessens E A, Cowell C A
Am J Obstet Gynecol. 1981 Feb 1;139(3):277-80. doi: 10.1016/0002-9378(81)90009-0.
Acute menorrhagia in adolescence is a much underestimated clinical problem, often requiring urgent medical intervention. In a 9-year case review between January, 1971, and January, 1980, we looked at all admissions to a children's hospital for acute menorrhagia, where genital tract pathology had been excluded. A primary coagulation disorder was found in almost 20% of these 59 patients. One quarter of those with severe menorrhagia (hemoglobin less than 10 gm/100 ml), one third of those requiring transfusion, and one half of those presenting at menarche had such an underlying disorder. Therefore, proper screening and therapy are essential in all girls with menorrhagia. Conventional methods of hormonal control are only partially effective in these special cases.
青春期急性月经过多是一个常被低估的临床问题，往往需要紧急医疗干预。在1971年1月至1980年1月的9年病例回顾中，我们研究了一家儿童医院所有因急性月经过多入院且已排除生殖道病理问题的病例。在这59例患者中，近20%被发现存在原发性凝血障碍。重度月经过多（血红蛋白低于10克/100毫升）的患者中有四分之一、需要输血的患者中有三分之一以及初潮时出现症状的患者中有一半存在这种潜在疾病。因此，对所有月经过多的女孩进行适当的筛查和治疗至关重要。在这些特殊病例中，传统的激素控制方法仅部分有效。
