Naukkarinen A, Arstila A U, Sorvari T E
Anat Rec. 1978 Aug;191(4):415-32. doi: 10.1002/ar.1091910403.
Morphological and functional differentiation of the mucosal surface epithelium of the bursa Fabricii was studied in White Leghorn chicken fetuses and newly hatched chickens. First signs of differentiation towards two types of epithelial cells appeared on the thirteenth day of incubation: The apical cells of the epithelial buds projected towards the lumen, and an increase in the number of Golgi regions was observed in the epithelial cells between the buds. On day 15 the follicle-associated epithelium contained small apically situated vacuoles, and large mucin granules appeared in the interfollicular surface epithelium. Towards the day of hatching both epithelial cell types were arranged to a monolayered or pseudostratified cylindrical epithelium. The follicle-associated epithelium had invaginations and small vacuoles in the apical cytoplasm, whereas the interfollicular surface epithelium had numerous microvilli on its apical surface and large mucin granules in the apical cytoplasm. In functional studies, endocytosis of colloidal carbon was demonstrated in four out of ten 19-day fetuses and in all chickens studied immediately after hatching.
在白来航鸡胎儿和新孵出的雏鸡中研究了法氏囊黏膜表面上皮的形态学和功能分化。在孵化第13天出现了向两种上皮细胞类型分化的最初迹象：上皮芽的顶端细胞向管腔突出，并且在芽之间的上皮细胞中观察到高尔基体区域数量增加。在第15天，滤泡相关上皮含有位于顶端的小液泡，并且在滤泡间表面上皮中出现大的粘蛋白颗粒。在孵化日时，两种上皮细胞类型均排列成单层或假复层柱状上皮。滤泡相关上皮在顶端细胞质中有内陷和小液泡，而滤泡间表面上皮在其顶端表面有许多微绒毛并且在顶端细胞质中有大的粘蛋白颗粒。在功能研究中，在10只19日龄胎儿中的4只以及在孵化后立即研究的所有雏鸡中均证实了胶体碳的内吞作用。
