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由不同b型流感嗜血杆菌菌株产生的两种荚膜多糖的结构研究。

Structural studies of two capsular polysaccharides elaborated by different strains of Haemophilus influenzae type e.

作者信息

Branefors-Helander P

出版信息

Carbohydr Res. 1981 Jan 15;88(1):77-84. doi: 10.1016/s0008-6215(00)84602-9.

DOI:10.1016/s0008-6215(00)84602-9
PMID:6970617
Abstract

The structures of two capsular polysaccharides elaborated by Haemophilus influenzae type e, strains NCTC 8455 and 8472, respectively, have been investigated, methylation analysis and n.m.r. spectrometry being the principal methods used. It is concluded that the polysaccharides are composed of repeating-units having the following structure: Formula: [See Text]. In the polysaccharide from strain NCTC 8472, all of the repeating-units contain the beta-D-fructofuranosyl group. The polysaccharide from strain NCTC 8455, however, contains only traces of D-fructose, corresponding to approximately one group per 100 repeating-units.

摘要

分别由e型流感嗜血杆菌NCTC 8455株和8472株产生的两种荚膜多糖的结构已被研究,甲基化分析和核磁共振光谱法是主要使用的方法。得出的结论是,这些多糖由具有以下结构的重复单元组成:分子式:[见正文]。在NCTC 8472株的多糖中,所有重复单元都含有β-D-呋喃果糖基。然而,NCTC 8455株的多糖仅含有痕量的D-果糖,相当于每100个重复单元中约有一个基团。

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