Shea J P, Berman J M, McReynolds G W
Otolaryngol Head Neck Surg (1979). 1980 Nov-Dec;88(6):681-3. doi: 10.1177/019459988008800609.
Over a three-day period, pharyngitis, neck swelling, deep voice, dysphagia, fever, and cellulitis of the anterior neck and upper chest developed in a 63-year-old woman. Sixteen hours following the institution of intravenous ampicillin, septic shock developed and the patient became comatose. Ampicillin-resistant Hemophilus influenzae type B was found in a culture taken from her blood and pharynx. In patients who have an upper respiratory tract infection and severe cellulitis of the neck, initial therapy should include chloramphenicol because of the possibility of ampicillin-resistant Hemophilus influenzae infection.
一名63岁女性在三天内出现了咽炎、颈部肿胀、声音低沉、吞咽困难、发热以及颈前部和上胸部蜂窝织炎。在静脉注射氨苄西林16小时后，发生了感染性休克，患者陷入昏迷。从她的血液和咽部培养物中发现了对氨苄西林耐药的B型流感嗜血杆菌。对于患有上呼吸道感染和颈部严重蜂窝织炎的患者，由于存在对氨苄西林耐药的流感嗜血杆菌感染的可能性，初始治疗应包括氯霉素。
