[HLA complexes and psoriatic rheumatism].

A study of the HLA system during psoriasis and psoriatic rheumatism demonstrated several genetic markers. The associations of psoriasis with antigens of locus B are feeble (HLA B 13, HLA B 17) or incontant (HLA B 37, HLA W 16). On the other hand, there existe a very strong link between psoriasis with an antigen of locus C (HLA CW6) found in all races and with antigens of locus C (HLA DMO, HLA DW 11). During psoriatic rheumatism, antigen HLA B27 is present mainly in the forms with spinal involvement. No peripheral marker of arthritis has been demonstrated until now, the increased frequency of BW 38 does not seem specific of the joint involvement.