Kornetsky C, Esposito R U
Brain Res. 1981 Mar 30;209(2):496-500. doi: 10.1016/0006-8993(81)90177-3.
The effects of cocaine on both rewarding and detection thresholds for intracranial stimulation to the same brain sites in the same animals were determined. The drug caused a dissociation in effects on the two types of brain stimulation. Detection threshold was elevated at doses of cocaine that lowered the reward threshold.
研究了可卡因对同一动物颅内刺激同一脑区的奖赏阈值和检测阈值的影响。该药物对两种类型的脑刺激产生了不同的作用。在降低奖赏阈值的可卡因剂量下,检测阈值升高。