Rose H D, Varkey B
Am Rev Respir Dis. 1978 Aug;118(2):403-8. doi: 10.1164/arrd.1978.118.2.403.
Two patients with second relapses of pulmonary blastomycosis after successful treatments with adequate doses of amphotericin B were retreated with miconazole. One patient had experienced an acute intrabronchial spread of disease to the contralateral lung before miconazole therapy. Marked clinical and roentgenographic improvement occurred with treatment, followed by mycologic relapse 1 month later. The other patient sustained a more indolent relapse of disease. A favorable response to treatment with miconazole was demonstrated by improvement in abnormalities noted on a chest roentgenogram and a [67]gallium-citrate scan.
两名患者在接受足量两性霉素B成功治疗后发生肺芽生菌病二次复发，随后接受咪康唑治疗。一名患者在咪康唑治疗前疾病出现急性支气管内播散至对侧肺。治疗后临床和影像学有明显改善，但1个月后出现真菌学复发。另一名患者疾病复发较为隐匿。胸部X线片和枸橼酸镓扫描显示的异常情况有所改善，表明对咪康唑治疗反应良好。
