Iavorkovskiĭ L I, Rotsena A Ia, Udris O Iu, Bliumental' R Ia, Zile M A
Vopr Onkol. 1981;27(4):34-9.
The paper deals with a comparison of the results of treatment of 19 patients with malignant lymphomas, mostly diffuse ones, stage 3, by POPP schedule (paphencyl, vincristine (oncovine), procarbosin (natulan) and prednisolone) and 37 similar patients who received a modified standard COPP treatment. Following six courses of POPP treatment, the frequency of complete remission was significantly higher (83 and 51% respectively). Therefore, this schedule of therapy may be recommended for a large-scale application. The assessment of the survival rates of patients who received either type of treatment required further study.
本文比较了采用POPP方案（甲基苄肼、长春新碱（安可平）、丙卡巴肼（纳治兰）和泼尼松龙）治疗19例恶性淋巴瘤患者（大多为弥漫性，3期）的结果，以及37例接受改良标准COPP治疗的类似患者的结果。经过六个疗程的POPP治疗后，完全缓解的频率显著更高（分别为83%和51%）。因此，该治疗方案可推荐大规模应用。对接受任何一种治疗的患者的生存率评估需要进一步研究。
