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[在高蛋白饮食和药物制剂联合治疗过程中,低度活动的风湿性患者的特异性和非特异性细胞溶解反应]

[Specific and nonspecific cytolysis reactions in rheumatic patients with a low degree of activity in the process of combined treatment by a high-protein diet and drug preparations].

作者信息

Samsonov M A, Sachkov V I, Voĭtko N E, Meshcheriakova V A, Sycheva A N

出版信息

Vopr Pitan. 1981 Mar-Apr(2):47-50.

PMID:6972671
Abstract

Effect of therapy including high-protein diet and hormones on specific and nonspecific cytolysis was studied in patients with torpid and latent-running recurrent rheumatic carditis. The number of HeLa cells on which specific antigens (cardiac tissue extract, collagen, group C streptococcal nucleoproteid) were adsorbed significantly decreased on addition to the test target sensitized lymphocytes from the patients examined. As a result of therapy most patients showed the reduced activity of supernatants obtained from peripheral blood lymphocyte cultures that were incubated with specific antigens.

摘要

在隐匿型和潜伏型复发性风湿性心炎患者中,研究了包括高蛋白饮食和激素在内的治疗对特异性和非特异性细胞溶解的影响。在加入来自受检患者的致敏淋巴细胞后,吸附有特异性抗原(心脏组织提取物、胶原蛋白、C 组链球菌核蛋白)的海拉细胞数量显著减少。治疗后,大多数患者与特异性抗原一起孵育的外周血淋巴细胞培养物上清液活性降低。

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