Zilch H
Handchirurgie. 1980;12(1-2):71-5.
An experiment on revascularization of glued osteochondral fragments was carried out. A chiseled part of the medial femoral condyle of the knee joint of the rabbit was fixed on the right side with an acryl adhesive and on the left side with a new fibrinogen adhesive system (FAS), consisting of highly concentrated fibrinogen, thrombin, and factor XIII. The animals were sacrificed after three, six, ten, and twenty eight days. The FAS is changed into granulation tissue rich in vessels and, therefore, there is a quick revascularization of the fragments soon after three days. On the contrary the acryl adhesive is a foreign body and prevents ingrowth of capillaries during the time of investigation. Immobilization with plaster is necessary to prevent the fragment from gliding off.
进行了一项关于粘合骨软骨碎片血管再生的实验。将兔膝关节股骨内侧髁凿下的部分,右侧用丙烯酸粘合剂固定,左侧用一种新的纤维蛋白原粘合剂系统(FAS)固定,该系统由高浓度纤维蛋白原、凝血酶和因子 XIII 组成。在三天、六天、十天和二十八天后处死动物。FAS 会转变为富含血管的肉芽组织,因此,三天后碎片很快就会有快速的血管再生。相反,丙烯酸粘合剂是一种异物,在研究期间会阻止毛细血管长入。用石膏固定是必要的,以防止碎片滑落。