Sarfeh I J, Tabak C, Eugene J, Juler G L
Ann Surg. 1981 Aug;194(2):149-51. doi: 10.1097/00000658-198108000-00006.
Since, in many patients with alcoholic liver disease and upper gastrointestinal hemorrhage, varices and erosive gastritis frequently coexist, the purpose of this study was to assess the severity of hemorrhage, rebleeding and mortality rates when these lesions are present singly or concomitantly. In 104 patients not operated upon, 31 had both lesions present on endoscopic examination, and their clinical courses paralleled the severity of 29 patients who had bleeding varices as the sole finding. In 13 patients with alcoholic liver disease and upper gastrointestinal hemorrhage who were found to have erosive gastritis as the sole lesion, the clinical course was as benign as in 31 patients with ethanol-induced gastritis without liver disease, and their blood loss, rebleeding and mortality rates were significantly less than in patients with both varices and gastritis. It is concluded that the course and prognosis of upper gastrointestinal hemorrhage in patients with alcoholic liver disease and erosive gastritis is dependent upon the presence or absence of gastroesophageal varices.
由于在许多患有酒精性肝病和上消化道出血的患者中，静脉曲张和糜烂性胃炎常常并存，本研究的目的是评估这些病变单独出现或同时存在时出血的严重程度、再出血情况及死亡率。在104例未接受手术的患者中，31例在内镜检查时两种病变均存在，他们的临床病程与29例仅发现静脉曲张出血的患者的严重程度相似。在13例患有酒精性肝病和上消化道出血且被发现仅患有糜烂性胃炎的患者中，临床病程与31例无肝病的乙醇性胃炎患者一样良性，他们的失血量、再出血率和死亡率显著低于同时患有静脉曲张和胃炎的患者。结论是，患有酒精性肝病和糜烂性胃炎的患者上消化道出血的病程和预后取决于是否存在胃食管静脉曲张。
