1977 - 1979年某流行地区伤寒沙门氏菌和甲型副伤寒沙门氏菌耐药性研究。

A study of drug resistance among Salmonella typhi and Salmonella paratyphi A in an endemic area, 1977-79.

作者信息

Rao R S, Sundararaj T, Subramanian S, Shankar V, Murty S A, Kapoor S C

出版信息

Trans R Soc Trop Med Hyg. 1981;75(1):21-4. doi: 10.1016/0035-9203(81)90008-0.

Abstract

Tests for antibiotic resistance were carried out on 198 strains of Salmonella typhi and S. paratyphi A isolated from cases of enteric fevers. Their minimal inhibitory concentrations for streptomycin, chloramphenicol, ampicillin, furazolidine and co-trimoxazole were estimated by plate dilution technique. Four strains of S. typhi and one strain of S. paratyphi A were found to show multiple resistance with a set pattern of resistance to chloramphenicol, streptomycin, sulphonamide, tetracycline and spectinomycin. All the five strains carried R-factors. Three of the resistant S. typhi belonged to Phage type 'O' and one was in Phage type 'A'. The single resistant S. paratyphi A belonged to Phage type '2'.

摘要

对从伤寒病例中分离出的198株伤寒沙门氏菌和甲型副伤寒沙门氏菌进行了抗生素耐药性检测。采用平板稀释技术测定了它们对链霉素、氯霉素、氨苄青霉素、呋喃唑酮和复方新诺明的最低抑菌浓度。发现4株伤寒沙门氏菌和1株甲型副伤寒沙门氏菌表现出多重耐药性，对氯霉素、链霉素、磺胺类、四环素和壮观霉素具有特定的耐药模式。所有这5株菌都携带R因子。3株耐药伤寒沙门氏菌属于噬菌体类型“O”，1株属于噬菌体类型“A”。唯一的耐药甲型副伤寒沙门氏菌属于噬菌体类型“2”。