The effects of piridinol carbamate on hypercholesteremia and aortal damage produced by 5 days' application of Altman's diet to the rat.

The Altman's diet applied for 5 days in rats produces hypercholesteremia and aortal degeneration with breaks of continuity of elastic fibres and deposition of calcium salts. Piridinol carbamate depresses the serum cholesterol level and given in a dose 3 mg/kg prevents the damage of elastic fibres.