Kuri J, Fernández de la Vega P, Attie F, Olvera E, Olvera S, Mispireta E
Arch Inst Cardiol Mex. 1978 May-Jun;48(3):612-30.
In a group of 564 patients with rheumatic heart disease seen in the period from 1971 to 1975, who were under benzatinic prophylaxis, 23% were seen in the clinic and 77% at home. The object of this revision is to analyze the latter group in order to obtain the frequency of pharyngoamigdaline infections, and of relapses. 1. During the observation, those patients who did not present pharyngeal infections had no relapses. On the other hand, all relapses were observed in those patients who presented infections. 2. Those patients who carried out the prophylaxis incorrectly and who also presented pharyngeal infections, had almost twice the percentage of relapses as those who carried out the prophylaxis correctly. 3. In the group with effective prophylaxis, including those cases with or without pharyngeal infection, 5% had recurrences. In the group with ineffective prophylaxis, 16% had relapses. 4. Those patients with subsequent attacks doubled the percentage of relapses in comparison with those with initial attacks. 5. The plurivalvular patients have a higher frequency of recurrences than the univalvular patients. 6. During the first year of post-attack prophylaxis, the incidence of relapses is only 1.7%, in comparison with the following years in which there is a higher incidence of around 10%. 7. The total number of recurrences in 564 patients was 8%.
在1971年至1975年期间接受苄星青霉素预防治疗的564例风湿性心脏病患者中,23%在诊所接受治疗,77%在家中接受治疗。本次回顾的目的是分析后一组患者,以得出咽扁桃体感染及复发的频率。1. 在观察期间,未出现咽部感染的患者无复发情况。另一方面,所有复发情况均出现在出现感染的患者中。2. 预防措施执行不当且出现咽部感染的患者,其复发率几乎是预防措施执行正确患者的两倍。3. 在预防措施有效的组中,包括有或无咽部感染的病例,5%出现复发。在预防措施无效的组中,16%出现复发。4. 与初次发作的患者相比,后续发作的患者复发率翻倍。5. 多瓣膜病患者的复发频率高于单瓣膜病患者。6. 在发作后预防的第一年,复发率仅为1.7%,而在随后几年中复发率较高,约为10%。7. 564例患者的总复发率为8%。