Alexander N J, Senner J W, Hoch E J
Int J Epidemiol. 1981 Sep;10(3):217-22. doi: 10.1093/ije/10.3.217.
We assessed the effect of vasectomy on blood pressure by collecting cross-sectional data on the systolic and diastolic blood pressure of 946 male volunteer blood donors; of these, 30% were vasectomized. We used analysis of multiple covariance to correct both pressures for variation in age, weight, and height. Vasectomized and nonvasectomized men did not differ significantly in mean systolic or diastolic blood pressures. However, many of these men had been vasectomized for only a short period of time. We analysed the vasectomy subsample by multiple regression to determine whether blood pressures adjusted for age, body mass index, and height changed with time since vasectomy and found a slight, but non-significant, rise in the systolic pressure with square of time since vasectomy. The data are sufficiently strong to raise concern that data from a sample of men who have been vasectomized for longer periods of time would have shown a more dramatic increase.
我们通过收集946名男性志愿献血者的收缩压和舒张压的横断面数据，评估了输精管切除术对血压的影响；其中30%的人接受了输精管切除术。我们使用多元协方差分析来校正年龄、体重和身高变化对这两种血压的影响。接受输精管切除术的男性和未接受输精管切除术的男性在平均收缩压或舒张压上没有显著差异。然而，这些男性中许多人接受输精管切除术的时间较短。我们通过多元回归分析输精管切除的子样本，以确定校正年龄、体重指数和身高后的血压是否随输精管切除后的时间而变化，结果发现收缩压随输精管切除后的时间平方略有上升，但不显著。现有数据足以引起人们的担忧，即来自接受输精管切除术时间更长的男性样本的数据可能会显示出更显著的血压升高。
