Smolik R, Knapikowa D, Kwiatkowski S
Med Pr. 1981;32(3):183-6.
The level of alpha 1-antitrypsin in blood serum in copper miners was examined. Among 278 subjects not a single case of total insufficiency was found, whereas the partial insufficiency of this inhibitor was found in 4.3% of subjects. The studies of the total correlation indicated high indices of the ratio between alpha 1-antitrypsin level and lungs vital capacity in those with bronchitis, which would suggest that the decreased efficiency of the respiratory tract results form the hereditary insufficiency of this inhibitor.
对铜矿工人血清中的α1 -抗胰蛋白酶水平进行了检测。在278名受试者中,未发现一例完全缺乏的情况,而该抑制剂部分缺乏的情况在4.3%的受试者中被发现。总体相关性研究表明,支气管炎患者中α1 -抗胰蛋白酶水平与肺肺活量之比的指数较高,这表明呼吸道效率降低是由该抑制剂的遗传性缺乏所致。