Osborne D, Jaszczak R, Coleman R E, Drayer B
J Comput Assist Tomogr. 1981 Oct;5(5):684-9. doi: 10.1097/00004728-198110000-00016.
A whole body single photon emission computed tomographic system (SPECT) has been used to investigate canine pulmonary perfusion utilizing 99mTc-microspheres and has been compared to conventional radionuclide pulmonary perfusion studies. The SPECT data were reconstructed and displayed in 32 transverse, 16 sagittal, and 16 coronal plane sections, producing additional anatomical information on the pattern of pulmonary perfusion compared to that available with the conventional perfusion scan. The major bronchi, the major blood vessels, and the pulmonary hila are readily seen on the SPECT examination (confirmed anatomically) but are not easily identified on a conventional lung scan. Qualitative assessment of serial SPECT scans established that the distribution and relative concentration of infected radiopharmaceutical was consistent provided the studies had been performed with the animal in the same anatomical position. Changes in the dog's position resulted in a redistribution of radiopharmaceutical such that the most dependent lung contained the greatest concentration.
一种全身单光子发射计算机断层扫描系统（SPECT）已被用于利用99mTc-微球研究犬类肺灌注，并与传统放射性核素肺灌注研究进行了比较。SPECT数据被重建并显示在32个横断面、16个矢状面和16个冠状面切片中，与传统灌注扫描相比，产生了关于肺灌注模式的额外解剖学信息。在SPECT检查中（经解剖学证实）很容易看到主支气管、主要血管和肺门，但在传统肺部扫描中不容易识别。对连续SPECT扫描的定性评估表明，只要在相同解剖位置对动物进行研究，感染放射性药物的分布和相对浓度就是一致的。狗的体位变化导致放射性药物重新分布，使得最下垂的肺中放射性药物浓度最高。
