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[家禽淋巴肿瘤的比较病理学与病因学]

[Comparative pathology and etiology of lymphatic tumors in fowl].

作者信息

Beyer J

出版信息

Arch Exp Veterinarmed. 1978;32(3):441-8.

PMID:697529
Abstract

The tumours associated to lymphoid leucosis and Marek's disease are compared with lymphoproliferative diseases of man and other species, by morphological, immunomorphological, and aetiological criteria. Morphological and immunomorphological similarities were found to exist between lymphoid leucosis and malignant lymphomas of the B-cell system in man, more particularly, follicular lymphoma, lamphoblastic lymphosarcoma of the B-cell type, Burkitt's lymphoma, and immunoblastic lymphoma. Equivalent similarities with Marek's disease are relating particularly to Hodgkin's disease, infectious mononucleosis, and malignant lymphomas of the T-cell system. Aetiological relations were found to exist between lymphoid leucosis and the oncorna-virus-dependent lymphatic tumours in mammals, while similarities with Marek's disease were relating to infectious mononucleosis, Burkitt's lymphoma, and herpes-virus-dependent lymphatic tumours in monkey. Reference is made to the model nature of both lymphoid leucosis and Marek's disease and the resulting relevance to tumour research.

摘要

通过形态学、免疫形态学和病因学标准,将与淋巴细胞性白血病和马立克氏病相关的肿瘤与人类及其他物种的淋巴增殖性疾病进行比较。发现淋巴细胞性白血病与人类B细胞系统的恶性淋巴瘤,特别是滤泡性淋巴瘤、B细胞型成淋巴细胞性淋巴肉瘤、伯基特淋巴瘤和免疫母细胞性淋巴瘤之间存在形态学和免疫形态学相似性。与马立克氏病的等效相似性尤其与霍奇金病、传染性单核细胞增多症和T细胞系统的恶性淋巴瘤有关。发现淋巴细胞性白血病与哺乳动物中依赖肿瘤RNA病毒的淋巴肿瘤之间存在病因学关系,而与马立克氏病的相似性则与传染性单核细胞增多症、伯基特淋巴瘤以及猴子中依赖疱疹病毒的淋巴肿瘤有关。文中提到了淋巴细胞性白血病和马立克氏病的模型性质及其与肿瘤研究的相关性。

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