Hall R J, Swineford D M
Toxicol Lett. 1981 Aug;8(6):331-6. doi: 10.1016/0378-4274(81)90122-3.
Seven species of amphibian larvae were exposed to toxaphene and endrin in a continuous-flow dosing system to determine differences in sensitivity to the two compounds, EC50 and LC50 estimates varied from those for Rana sphenocephala by no more than one order of magnitude when calculated on the basis of intended concentrations. Removal of pesticides from water by the test animals was significant and it makes interpretation of results difficult. Continuous-flow toxicity tests conflict with the adaptations of amphibian larvae for static water; use of such tests for amphibians requires further evaluation.
在连续流动给药系统中，将七种两栖类幼虫暴露于毒杀芬和异狄氏剂中，以确定对这两种化合物敏感性的差异。根据预期浓度计算时，EC50和LC50估计值与大头蛙的估计值相差不超过一个数量级。试验动物对水中农药的去除作用显著，这使得结果的解释变得困难。连续流动毒性试验与两栖类幼虫适应静态水的特性相冲突；将此类试验用于两栖类动物需要进一步评估。
