Whelan C A
Immunol Lett. 1981 Oct;3(4):249-54. doi: 10.1016/0165-2478(81)90083-3.
The essential findings in this paper are that ox erythrocytes (ORBC) sensitized with human heterophile IgM antibody failed to detect Fc mu receptors on human lymphocytes. These results contrast to those obtained when the ORBC were sensitized with mouse hybridoma IgM antibody (SCC I). It is therefore suggested that the functional role of Fc mu receptors on human lymphocytes is not to bind IgM/antigen complexes.
本文的主要发现是，用人嗜异性IgM抗体致敏的牛红细胞（ORBC）未能检测到人类淋巴细胞上的Fcμ受体。这些结果与用小鼠杂交瘤IgM抗体（SCC I）致敏ORBC时获得的结果形成对比。因此，有人提出人类淋巴细胞上Fcμ受体的功能作用不是结合IgM/抗原复合物。
