Perov Iu L
Arkh Anat Gistol Embriol. 1978 Aug;75(8):50-5.
Ultrastructure of sinuous proximal and straight distal tubules, as well as collecting tubules of the cortical layer in the rat kidney fixed with perfusion has been studied with electron microscopic morphometry 7--8 weeks after contralateral nephrectomy. The volume of mitochondria, the area of their crisis, the area of the membranes in intracellular labyrinth and other morphometrical parameters have been calculated. Relative volume of mitochondria in the nephron areas studied does not change, while in the collecting tubules it is elevated. The area of crisis in mitochondria and "coefficient of morphological organization level" of these organells in the proximal tubules are increased, in the distal do not change, in the collecting tubules increase again. Subcellular changes described are discussed mainly in terms of enhancement of concentrating function of the compensatory-hypertrophic kidney.
在对大鼠进行对侧肾切除7 - 8周后,采用电子显微镜形态计量学方法研究了经灌注固定的大鼠肾脏皮质层中迂曲的近端小管、直的远端小管以及集合小管的超微结构。计算了线粒体的体积、其嵴的面积、细胞内迷路中膜的面积以及其他形态计量学参数。在所研究的肾单位区域中,线粒体的相对体积没有变化,而在集合小管中则有所升高。近端小管中线粒体嵴的面积以及这些细胞器的“形态组织水平系数”增加,远端小管中不变,集合小管中再次增加。所描述的亚细胞变化主要从代偿性肥大肾脏浓缩功能增强的角度进行了讨论。