Wolpert S M, Barnett F J, Prager R J
AJR Am J Roentgenol. 1982 Jan;138(1):99-102. doi: 10.2214/ajr.138.1.99.
Embolization may be the primary and exclusive treatment of cerebral arteriovenous malformations. To evaluate its benefits, a group of 27 patients was studied for the incidence of hemorrhages, headaches, seizures, and neurologic deficits, both before and after Silastic sphere embolization. Questionnaires to patients and physicians were used. Embolization was found to decrease the frequency of headaches in most patients with this symptom, but had no effect on the frequency of seizures when patients in whom medical therapy was altered were excluded nor on the progression or incidence of neurologic signs and symptoms. The effect of embolization on the incidence of recurrent hemorrhages is as yet undetermined.
栓塞术可能是脑动静脉畸形的主要且唯一的治疗方法。为评估其疗效，对一组27例患者在使用硅橡胶球囊栓塞术前后的出血、头痛、癫痫发作及神经功能缺损的发生率进行了研究。采用了向患者和医生发放问卷的方式。结果发现，栓塞术可降低大多数有此症状患者的头痛频率，但排除改变药物治疗的患者后，对癫痫发作频率以及神经体征和症状的进展或发生率并无影响。栓塞术对复发性出血发生率的影响尚不确定。
