Tsung S H, Lin J I
Ann Clin Lab Sci. 1981 Nov-Dec;11(6):542-5.
The premise that chronic antigenic stimulation may be involved in lymphoproliferative disorders was considered in a patient with angioimmunoblastic lymphadenopathy who had received diphenylhydantoin (DPH) for seizure. This patient had clinical features overlapping with systemic lupus erythematosus (SLE) and serum antibody directed against DPH. It was proposed that the syndrome was caused by chronic antigenic stimulation with DPH.
一名患有血管免疫母细胞性淋巴结病且因癫痫接受过苯妥英(DPH)治疗的患者,其慢性抗原刺激可能与淋巴增生性疾病有关这一假设得到了考量。该患者具有与系统性红斑狼疮(SLE)重叠的临床特征以及针对DPH的血清抗体。有人提出该综合征是由DPH的慢性抗原刺激所致。