Chiazze L, Ference L D
Environ Health Perspect. 1981 Oct;41:137-43. doi: 10.1289/ehp.8141137.
The results of a cross-sectional mortality study of 3847 deaths occurring among current and former (white) employees of 17 PVC fabricators during 1964-1973 are presented. Sex-race-cause-specific proportionate mortality ratios (PMR's) were computed by using two separate standards: one, the U.S. mortality in 1968; the second, U.S. mortality for the individual years 1964-1973. In addition, a case-control analysis, based upon 44 breast cancer deaths among white female employees, is presented. PMR's are significantly different from unity for all cancers, and for cancers of the digestive system among both white males and white females. Although observed deaths significantly exceeded expectations for cancer of the breast, a subsequent case-control analysis reveals no statistically significant relative risks for breast cancer.
本文呈现了一项横断面死亡率研究的结果，该研究针对1964年至1973年间17家聚氯乙烯制造商的在职及离职（白人）员工中发生的3847例死亡案例。通过使用两个不同的标准计算了性别-种族-病因特异性比例死亡率（PMR）：一个是1968年的美国死亡率；另一个是1964年至1973年各年份的美国死亡率。此外，还给出了基于白人女性员工中44例乳腺癌死亡案例的病例对照分析。所有癌症以及白人男性和白人女性的消化系统癌症的PMR均显著不同于1。尽管观察到的乳腺癌死亡人数显著超过预期，但随后的病例对照分析显示，乳腺癌不存在统计学上显著的相对风险。
